S14R (p.Ser14Arg) variant of IRS2 (Insulin receptor substrate 2)
S14R (p.Ser14Arg) in IRS2 (Insulin receptor substrate 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
S14R (p.Ser14Arg) variant details
- p.Ser14Arg
- Ensembl rs1877912890
- Missense
- Variant Prioritization Score for Impact Estimate 0.266
- REVEL 0.04
- CADD 6.67
- PolyPhen-2 0.00
- SIFT 0.23
- Population evidence available
- Structural context available