S14N (p.Ser14Asn) variant of IRS2 (Insulin receptor substrate 2)
S14N (p.Ser14Asn) in IRS2 (Insulin receptor substrate 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
S14N (p.Ser14Asn) variant details
- p.Ser14Asn
- TOPMed rs1309855258
- gnomAD rs1309855258
- Missense
- Variant Prioritization Score for Impact Estimate 0.0963
- REVEL 0.04
- CADD 3.01
- PolyPhen-2 0.00
- SIFT 0.34
- Population evidence available
- Structural context available