S14G (p.Ser14Gly) variant of IRS2 (Insulin receptor substrate 2)
S14G (p.Ser14Gly) in IRS2 (Insulin receptor substrate 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
S14G (p.Ser14Gly) variant details
- p.Ser14Gly
- Ensembl rs1877913046
- Missense
- Variant Prioritization Score for Impact Estimate 0.152
- REVEL 0.03
- CADD 5.41
- PolyPhen-2 0.00
- SIFT 0.52
- Population evidence available
- Structural context available