R38H (p.Arg38His) variant of IRS2 (Insulin receptor substrate 2)
R38H (p.Arg38His) in IRS2 (Insulin receptor substrate 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
R38H (p.Arg38His) variant details
- p.Arg38His
- Ensembl rs2138939667
- Missense
- Variant Prioritization Score for Impact Estimate 0.447
- REVEL 0.31
- CADD 23.30
- PolyPhen-2 0.36
- SIFT 0.00
- Population evidence available
- Structural context available