R32H (p.Arg32His) variant of IRS2 (Insulin receptor substrate 2)
R32H (p.Arg32His) in IRS2 (Insulin receptor substrate 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
R32H (p.Arg32His) variant details
- p.Arg32His
- Ensembl rs2138939710
- Missense
- Variant Prioritization Score for Impact Estimate 0.441
- REVEL 0.29
- CADD 24.30
- PolyPhen-2 0.62
- SIFT 0.00
- Population evidence available
- Structural context available