Q69K (p.Gln69Lys) variant of IRS2 (Insulin receptor substrate 2)
Q69K (p.Gln69Lys) in IRS2 (Insulin receptor substrate 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
Q69K (p.Gln69Lys) variant details
- p.Gln69Lys
- gnomAD rs1438789170
- Missense
- Variant Prioritization Score for Impact Estimate 0.23
- REVEL 0.04
- CADD 20.20
- PolyPhen-2 0.04
- SIFT 0.29
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available