Q40R (p.Gln40Arg) variant of IRS2 (Insulin receptor substrate 2)
Q40R (p.Gln40Arg) in IRS2 (Insulin receptor substrate 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
Q40R (p.Gln40Arg) variant details
- p.Gln40Arg
- Ensembl rs2138939648
- Missense
- Variant Prioritization Score for Impact Estimate 0.403
- REVEL 0.36
- CADD 25.20
- PolyPhen-2 0.79
- SIFT 0.01
- Population evidence available
- Structural context available