P68S (p.Pro68Ser) variant of IRS2 (Insulin receptor substrate 2)
P68S (p.Pro68Ser) in IRS2 (Insulin receptor substrate 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
P68S (p.Pro68Ser) variant details
- p.Pro68Ser
- Ensembl rs1877905789
- Missense
- Variant Prioritization Score for Impact Estimate 0.169
- REVEL 0.03
- CADD 19.10
- PolyPhen-2 0.10
- SIFT 0.57
- Population evidence available
- Structural context available