P4S (p.Pro4Ser) variant of IRS2 (Insulin receptor substrate 2)
P4S (p.Pro4Ser) in IRS2 (Insulin receptor substrate 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
P4S (p.Pro4Ser) variant details
- p.Pro4Ser
- Ensembl rs2138940037
- Missense
- Variant Prioritization Score for Impact Estimate 0.174
- REVEL 0.04
- CADD 21.90
- PolyPhen-2 0.06
- SIFT 0.01
- Population evidence available
- Structural context available