N28H (p.Asn28His) variant of IRS2 (Insulin receptor substrate 2)
N28H (p.Asn28His) in IRS2 (Insulin receptor substrate 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
N28H (p.Asn28His) variant details
- p.Asn28His
- ExAC rs769951329
- TOPMed rs769951329
- gnomAD rs769951329
- Missense
- Variant Prioritization Score for Impact Estimate 0.119
- REVEL 0.07
- CADD 15.70
- PolyPhen-2 0.00
- SIFT 0.34
- Most common in the REMAINING population (allele frequency 0.00049)
- Structural context available