N24S (p.Asn24Ser) variant of IRS2 (Insulin receptor substrate 2)
N24S (p.Asn24Ser) in IRS2 (Insulin receptor substrate 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
N24S (p.Asn24Ser) variant details
- p.Asn24Ser
- gnomAD rs1877911894
- Missense
- Variant Prioritization Score for Impact Estimate 0.195
- REVEL 0.07
- CADD 15.60
- PolyPhen-2 0.00
- SIFT 0.48
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available