N22S (p.Asn22Ser) variant of IRS2 (Insulin receptor substrate 2)

N22S (p.Asn22Ser) in IRS2 (Insulin receptor substrate 2) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.

N22S (p.Asn22Ser) variant details