N21S (p.Asn21Ser) variant of IRS2 (Insulin receptor substrate 2)
N21S (p.Asn21Ser) in IRS2 (Insulin receptor substrate 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
N21S (p.Asn21Ser) variant details
- p.Asn21Ser
- Ensembl rs2138939842
- Missense
- Variant Prioritization Score for Impact Estimate 0.16
- REVEL 0.08
- CADD 7.71
- PolyPhen-2 0.05
- SIFT 1.00
- Population evidence available
- Structural context available