N21K (p.Asn21Lys) variant of IRS2 (Insulin receptor substrate 2)
N21K (p.Asn21Lys) in IRS2 (Insulin receptor substrate 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
N21K (p.Asn21Lys) variant details
- p.Asn21Lys
- Ensembl rs2138939839
- Missense
- Variant Prioritization Score for Impact Estimate 0.132
- REVEL 0.03
- CADD 13.80
- PolyPhen-2 0.10
- SIFT 0.72
- Population evidence available
- Structural context available