N19S (p.Asn19Ser) variant of IRS2 (Insulin receptor substrate 2)
N19S (p.Asn19Ser) in IRS2 (Insulin receptor substrate 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
N19S (p.Asn19Ser) variant details
- p.Asn19Ser
- Ensembl rs2138939859
- Missense
- Variant Prioritization Score for Impact Estimate 0.246
- REVEL 0.07
- CADD 11.50
- PolyPhen-2 0.08
- SIFT 0.62
- Population evidence available
- Structural context available