K45* (p.Lys45Ter) variant of IRS2 (Insulin receptor substrate 2)

K45* (p.Lys45Ter) in IRS2 (Insulin receptor substrate 2) is a protein-truncating change. Clinical records from UniProt describe it as variant assessed as somatic; high impact. The record also includes structural context.

K45* (p.Lys45Ter) variant details