K41Q (p.Lys41Gln) variant of IRS2 (Insulin receptor substrate 2)
K41Q (p.Lys41Gln) in IRS2 (Insulin receptor substrate 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
K41Q (p.Lys41Gln) variant details
- p.Lys41Gln
- TOPMed rs1327405067
- gnomAD rs1327405067
- Missense
- Variant Prioritization Score for Impact Estimate 0.426
- REVEL 0.40
- CADD 26.10
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available