K33E (p.Lys33Glu) variant of IRS2 (Insulin receptor substrate 2)
K33E (p.Lys33Glu) in IRS2 (Insulin receptor substrate 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
K33E (p.Lys33Glu) variant details
- p.Lys33Glu
- Ensembl rs2138939708
- Missense
- Variant Prioritization Score for Impact Estimate 0.464
- REVEL 0.42
- CADD 23.70
- PolyPhen-2 0.30
- SIFT 0.00
- Population evidence available
- Structural context available