G57D (p.Gly57Asp) variant of IRS2 (Insulin receptor substrate 2)
G57D (p.Gly57Asp) in IRS2 (Insulin receptor substrate 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
G57D (p.Gly57Asp) variant details
- p.Gly57Asp
- TOPMed rs1248043947
- gnomAD rs1248043947
- Missense
- Variant Prioritization Score for Impact Estimate 0.254
- REVEL 0.15
- CADD 15.00
- PolyPhen-2 0.16
- SIFT 0.22
- Population evidence available
- Structural context available