G43V (p.Gly43Val) variant of IRS2 (Insulin receptor substrate 2)
G43V (p.Gly43Val) in IRS2 (Insulin receptor substrate 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
G43V (p.Gly43Val) variant details
- p.Gly43Val
- TOPMed rs1284382975
- gnomAD rs1284382975
- Missense
- Variant Prioritization Score for Impact Estimate 0.435
- REVEL 0.37
- CADD 22.40
- PolyPhen-2 0.03
- SIFT 0.03
- Population evidence available
- Structural context available