G35D (p.Gly35Asp) variant of IRS2 (Insulin receptor substrate 2)
G35D (p.Gly35Asp) in IRS2 (Insulin receptor substrate 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.80 / 1. The record also includes population frequency data and structural context.
G35D (p.Gly35Asp) variant details
- p.Gly35Asp
- Ensembl rs866827171
- Missense
- Variant Prioritization Score for Impact Estimate 0.804
- REVEL 0.91
- CADD 25.00
- PolyPhen-2 0.96
- SIFT 0.00
- Population evidence available
- Structural context available