G17S (p.Gly17Ser) variant of IRS2 (Insulin receptor substrate 2)
G17S (p.Gly17Ser) in IRS2 (Insulin receptor substrate 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
G17S (p.Gly17Ser) variant details
- p.Gly17Ser
- TOPMed rs1476561196
- gnomAD rs1476561196
- Missense
- Variant Prioritization Score for Impact Estimate 0.241
- REVEL 0.07
- CADD 17.50
- PolyPhen-2 0.03
- SIFT 0.15
- Population evidence available
- Structural context available