G11W (p.Gly11Trp) variant of IRS2 (Insulin receptor substrate 2)
G11W (p.Gly11Trp) in IRS2 (Insulin receptor substrate 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
G11W (p.Gly11Trp) variant details
- p.Gly11Trp
- Ensembl rs2138939958
- Missense
- Variant Prioritization Score for Impact Estimate 0.218
- REVEL 0.08
- CADD 17.30
- PolyPhen-2 0.39
- SIFT 0.02
- Population evidence available
- Structural context available