F47V (p.Phe47Val) variant of IRS2 (Insulin receptor substrate 2)
F47V (p.Phe47Val) in IRS2 (Insulin receptor substrate 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and structural context.
F47V (p.Phe47Val) variant details
- p.Phe47Val
- Ensembl rs2138939593
- Missense
- Variant Prioritization Score for Impact Estimate 0.553
- REVEL 0.63
- CADD 24.50
- PolyPhen-2 0.38
- SIFT 0.00
- Population evidence available
- Structural context available