F47S (p.Phe47Ser) variant of IRS2 (Insulin receptor substrate 2)
F47S (p.Phe47Ser) in IRS2 (Insulin receptor substrate 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
F47S (p.Phe47Ser) variant details
- p.Phe47Ser
- Ensembl rs2138939586
- Missense
- Variant Prioritization Score for Impact Estimate 0.591
- REVEL 0.62
- CADD 26.10
- PolyPhen-2 0.66
- SIFT 0.00
- Population evidence available
- Structural context available