D16Y (p.Asp16Tyr) variant of IRS2 (Insulin receptor substrate 2)
D16Y (p.Asp16Tyr) in IRS2 (Insulin receptor substrate 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
D16Y (p.Asp16Tyr) variant details
- p.Asp16Tyr
- Ensembl rs2138939892
- Missense
- Variant Prioritization Score for Impact Estimate 0.235
- REVEL 0.08
- CADD 21.70
- PolyPhen-2 0.03
- SIFT 0.01
- Population evidence available
- Structural context available