D16E (p.Asp16Glu) variant of IRS2 (Insulin receptor substrate 2)
D16E (p.Asp16Glu) in IRS2 (Insulin receptor substrate 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
D16E (p.Asp16Glu) variant details
- p.Asp16Glu
- ExAC rs749425733
- gnomAD rs749425733
- Missense
- Variant Prioritization Score for Impact Estimate 0.309
- REVEL 0.08
- CADD 13.20
- PolyPhen-2 0.01
- SIFT 0.29
- Population evidence available
- Structural context available