A60S (p.Ala60Ser) variant of IRS2 (Insulin receptor substrate 2)
A60S (p.Ala60Ser) in IRS2 (Insulin receptor substrate 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
A60S (p.Ala60Ser) variant details
- p.Ala60Ser
- Ensembl rs2138939484
- Missense
- Variant Prioritization Score for Impact Estimate 0.168
- REVEL 0.01
- CADD 15.20
- PolyPhen-2 0.07
- SIFT 0.11
- Population evidence available
- Structural context available