A55G (p.Ala55Gly) variant of IRS2 (Insulin receptor substrate 2)
A55G (p.Ala55Gly) in IRS2 (Insulin receptor substrate 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
A55G (p.Ala55Gly) variant details
- p.Ala55Gly
- ExAC rs758017473
- TOPMed rs758017473
- gnomAD rs758017473
- Missense
- Variant Prioritization Score for Impact Estimate 0.163
- REVEL 0.04
- CADD 15.80
- PolyPhen-2 0.01
- SIFT 0.31
- Most common in the Non-Finnish European population (allele frequency 9.4e-07)
- Structural context available