Y107* (p.Tyr107Ter) variant of IRS1 (Insulin receptor substrate 1)
Y107* (p.Tyr107Ter) in IRS1 (Insulin receptor substrate 1) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data.
Y107* (p.Tyr107Ter) variant details
- p.Tyr107Ter
- gnomAD rs1211505539
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.546
- CADD 37.00
- Most common in the African/African-American population (allele frequency 0.00041)