S105R (p.Ser105Arg) variant of IRS1 (Insulin receptor substrate 1)
S105R (p.Ser105Arg) in IRS1 (Insulin receptor substrate 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data.
S105R (p.Ser105Arg) variant details
- p.Ser105Arg
- TOPMed rs1939799305
- Missense
- Variant Prioritization Score for Impact Estimate 0.486
- REVEL 0.39
- CADD 24.10
- Most common in the African/African-American population (allele frequency 0.00031)