P41Q (p.Pro41Gln) variant of IRS1 (Insulin receptor substrate 1)
P41Q (p.Pro41Gln) in IRS1 (Insulin receptor substrate 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.73 / 1. The record also includes population frequency data.
P41Q (p.Pro41Gln) variant details
- p.Pro41Gln
- ExAC rs747512782
- TOPMed rs747512782
- gnomAD rs747512782
- Missense
- Variant Prioritization Score for Impact Estimate 0.728
- REVEL 0.73
- CADD 24.60
- PolyPhen-2 0.19
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)