N73T (p.Asn73Thr) variant of IRS1 (Insulin receptor substrate 1)
N73T (p.Asn73Thr) in IRS1 (Insulin receptor substrate 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data.
N73T (p.Asn73Thr) variant details
- p.Asn73Thr
- ExAC rs764972527
- TOPMed rs764972527
- gnomAD rs764972527
- Missense
- Variant Prioritization Score for Impact Estimate 0.571
- REVEL 0.52
- CADD 27.30
- PolyPhen-2 0.54
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 1.7e-05)