K79R (p.Lys79Arg) variant of IRS1 (Insulin receptor substrate 1)
K79R (p.Lys79Arg) in IRS1 (Insulin receptor substrate 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data.
K79R (p.Lys79Arg) variant details
- p.Lys79Arg
- TOPMed rs1288365568
- gnomAD rs1288365568
- Missense
- Variant Prioritization Score for Impact Estimate 0.524
- REVEL 0.43
- CADD 28.20
- PolyPhen-2 0.57
- SIFT 0.00
- Most common in the HGDP:FRENCH population (allele frequency 0.019)