G119A (p.Gly119Ala) variant of IRS1 (Insulin receptor substrate 1)
G119A (p.Gly119Ala) in IRS1 (Insulin receptor substrate 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data.
G119A (p.Gly119Ala) variant details
- p.Gly119Ala
- ESP rs372506005
- ExAC rs372506005
- TOPMed rs372506005
- gnomAD rs372506005
- Missense
- Variant Prioritization Score for Impact Estimate 0.163
- REVEL 0.03
- CADD 14.60
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the REMAINING population (allele frequency 0.00048)