F93L (p.Phe93Leu) variant of IRS1 (Insulin receptor substrate 1)
F93L (p.Phe93Leu) in IRS1 (Insulin receptor substrate 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data.
F93L (p.Phe93Leu) variant details
- p.Phe93Leu
- ExAC rs749548805
- gnomAD rs749548805
- Missense
- Variant Prioritization Score for Impact Estimate 0.415
- REVEL 0.55
- CADD 22.80
- PolyPhen-2 0.39
- SIFT 0.00
- Most common in the 1KG:MXL population (allele frequency 0.0081)