D98V (p.Asp98Val) variant of IRS1 (Insulin receptor substrate 1)
D98V (p.Asp98Val) in IRS1 (Insulin receptor substrate 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.80 / 1. The record also includes population frequency data.
D98V (p.Asp98Val) variant details
- p.Asp98Val
- ExAC rs756094077
- gnomAD rs756094077
- Missense
- Variant Prioritization Score for Impact Estimate 0.804
- REVEL 0.90
- CADD 29.90
- PolyPhen-2 0.96
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 1.7e-05)