W70* (p.Trp70Ter) variant of IRF7 (Interferon regulatory factor 7)
W70* (p.Trp70Ter) in IRF7 (Interferon regulatory factor 7) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.85 / 1. The record also includes population frequency data and structural context.
W70* (p.Trp70Ter) variant details
- p.Trp70Ter
- TOPMed rs1056641712
- gnomAD rs1056641712
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.851
- CADD 38.00
- Most common in the African/African-American population (allele frequency 3.1e-05)
- Structural context available