V65L (p.Val65Leu) variant of IRF7 (Interferon regulatory factor 7)
V65L (p.Val65Leu) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
V65L (p.Val65Leu) variant details
- p.Val65Leu
- gnomAD rs1464411215
- Missense
- Variant Prioritization Score for Impact Estimate 0.449
- AlphaMissense 0.37
- MetaLR 0.84
- MetaSVM 0.38
- CADD 15.40
- PolyPhen-2 0.89
- SIFT 0.02
- Most common in the Finnish in Finland (FIN) population (allele frequency 2.7e-05)
- Structural context available