T93P (p.Thr93Pro) variant of IRF7 (Interferon regulatory factor 7)
T93P (p.Thr93Pro) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.76 / 1. The record also includes population frequency data and structural context.
T93P (p.Thr93Pro) variant details
- p.Thr93Pro
- TOPMed rs953876367
- gnomAD rs953876367
- Missense
- Variant Prioritization Score for Impact Estimate 0.762
- AlphaMissense 0.93
- MetaLR 0.96
- MetaSVM 1.07
- CADD 29.10
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 4.8e-05)
- Structural context available