T85S (p.Thr85Ser) variant of IRF7 (Interferon regulatory factor 7)
T85S (p.Thr85Ser) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
T85S (p.Thr85Ser) variant details
- p.Thr85Ser
- TOPMed rs1285426444
- gnomAD rs1285426444
- Missense
- Variant Prioritization Score for Impact Estimate 0.363
- AlphaMissense 0.10
- MetaLR 0.63
- MetaSVM 0.04
- CADD 6.27
- PolyPhen-2 0.00
- SIFT 0.50
- Population evidence available
- Structural context available