T102R (p.Thr102Arg) variant of IRF7 (Interferon regulatory factor 7)
T102R (p.Thr102Arg) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.82 / 1. The record also includes population frequency data and structural context.
T102R (p.Thr102Arg) variant details
- p.Thr102Arg
- ExAC rs754717443
- TOPMed rs754717443
- gnomAD rs754717443
- Missense
- Variant Prioritization Score for Impact Estimate 0.82
- AlphaMissense 0.86
- MetaLR 0.94
- MetaSVM 1.06
- CADD 26.60
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available