S74I (p.Ser74Ile) variant of IRF7 (Interferon regulatory factor 7)
S74I (p.Ser74Ile) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
S74I (p.Ser74Ile) variant details
- p.Ser74Ile
- gnomAD rs1278054382
- Missense
- Variant Prioritization Score for Impact Estimate 0.404
- AlphaMissense 0.20
- MetaLR 0.76
- MetaSVM 0.27
- CADD 5.37
- PolyPhen-2 0.37
- SIFT 0.02
- Population evidence available
- Structural context available