S73T (p.Ser73Thr) variant of IRF7 (Interferon regulatory factor 7)
S73T (p.Ser73Thr) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
S73T (p.Ser73Thr) variant details
- p.Ser73Thr
- ExAC rs748320261
- gnomAD rs748320261
- Missense
- Variant Prioritization Score for Impact Estimate 0.486
- AlphaMissense 0.12
- MetaLR 0.83
- MetaSVM 0.33
- CADD 13.70
- PolyPhen-2 0.43
- SIFT 0.14
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available