S24T (p.Ser24Thr) variant of IRF7 (Interferon regulatory factor 7)
S24T (p.Ser24Thr) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.75 / 1. The record also includes population frequency data and structural context.
S24T (p.Ser24Thr) variant details
- p.Ser24Thr
- gnomAD rs1362327953
- Missense
- Variant Prioritization Score for Impact Estimate 0.749
- AlphaMissense 0.20
- MetaLR 0.95
- MetaSVM 1.07
- CADD 22.50
- PolyPhen-2 0.98
- SIFT 0.41
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available