S23N (p.Ser23Asn) variant of IRF7 (Interferon regulatory factor 7)
S23N (p.Ser23Asn) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
S23N (p.Ser23Asn) variant details
- p.Ser23Asn
- cosmic curated COSV99042
- ExAC rs754397896
- TOPMed rs754397896
- gnomAD rs754397896
- Missense
- Variant Prioritization Score for Impact Estimate 0.516
- AlphaMissense 0.32
- MetaLR 0.83
- MetaSVM 0.48
- CADD 16.70
- PolyPhen-2 0.98
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available