S23G (p.Ser23Gly) variant of IRF7 (Interferon regulatory factor 7)
S23G (p.Ser23Gly) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
S23G (p.Ser23Gly) variant details
- p.Ser23Gly
- TOPMed rs1420766879
- gnomAD rs1420766879
- Missense
- Variant Prioritization Score for Impact Estimate 0.471
- AlphaMissense 0.16
- MetaLR 0.90
- MetaSVM 0.72
- CADD 23.20
- PolyPhen-2 1.00
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available