R7T (p.Arg7Thr) variant of IRF7 (Interferon regulatory factor 7)
R7T (p.Arg7Thr) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
R7T (p.Arg7Thr) variant details
- p.Arg7Thr
- ExAC rs773962790
- TOPMed rs773962790
- gnomAD rs773962790
- Missense
- Variant Prioritization Score for Impact Estimate 0.602
- AlphaMissense 0.17
- MetaLR 0.90
- MetaSVM 0.80
- CADD 18.80
- PolyPhen-2 0.98
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available