R7M (p.Arg7Met) variant of IRF7 (Interferon regulatory factor 7)
R7M (p.Arg7Met) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data and structural context.
R7M (p.Arg7Met) variant details
- p.Arg7Met
- ExAC rs773962790
- TOPMed rs773962790
- gnomAD rs773962790
- Missense
- Variant Prioritization Score for Impact Estimate 0.623
- AlphaMissense 0.44
- MetaLR 0.86
- MetaSVM 0.61
- CADD 19.80
- PolyPhen-2 1.00
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available