R7G (p.Arg7Gly) variant of IRF7 (Interferon regulatory factor 7)
R7G (p.Arg7Gly) in IRF7 (Interferon regulatory factor 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
R7G (p.Arg7Gly) variant details
- p.Arg7Gly
- TOPMed rs1367244124
- Missense
- Variant Prioritization Score for Impact Estimate 0.398
- AlphaMissense 0.09
- MetaLR 0.79
- MetaSVM 0.12
- CADD 13.80
- PolyPhen-2 0.02
- SIFT 0.29
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available